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Anti Convulsants
    Home > Anti Convulsants > Pregalin (Pregabalin, Lyrica)
 

Pregalin (Pregabalin, Lyrica)

Select Ref Description Manufacturer Pack Size Strength Our Price
P875 Pregalin (Pregabalin, Lyrica) Torrent 10 caps 75 mg $ 10.53
P876 Pregalin (Pregabalin, Lyrica) Torrent 10 caps 150 mg $ 14.71
Price is per pack & not per tab.. eg: if pack size is 10 tabs & price is $2.75 then for 100 tabs the price would be $27.50

What is pregabalin?


Pregabalin is an anti-epileptic drug, also called an anticonvulsant. It works by slowing down impulses in the brain that cause seizures. Pregabalin also affects chemicals in the brain that send pain signals across the nervous system.

Pregabalin is used to control seizures and to treat fibromyalgia. It is also used to treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) or herpes zoster (post-herpetic neuralgia).

Pregabalin may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about pregabalin?


You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

If you are taking pregabalin to prevent seizures, keep taking the medication even if you feel fine. You may have an increase in seizures if you stop taking pregabalin. Follow your doctor's instructions.

Do not change your dose of pregabalin without your doctor's advice. Tell your doctor if the medication does not seem to work as well in treating your condition.

If you stop taking pregabalin suddenly, your seizures may become worse or you may have withdrawal symptoms. Withdrawal symptoms include headache, sleep problems, nausea, and diarrhea. Do not stop using pregabalin suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely. Carry an ID card or wear a medical alert bracelet stating that you are taking pregabalin, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking a seizure medication.

What should I discuss with my healthcare provider before taking pregabalin?


You should not use this medication if you are allergic to pregabalin.

Before using pregabalin, tell your doctor if you are allergic to any drugs, or if you have:

congestive heart failure;

diabetes; or

kidney disease.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take pregabalin.

You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

If a man fathers a child while using this medication, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment.

It is not known whether pregabalin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 18 years old.

How should I take pregabalin?


Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medicine with a full glass of water. You may take pregabalin with or without food.

Do not change your dose of pregabalin without your doctor's advice. Tell your doctor if the medication does not seem to work as well in treating your condition.

If you are taking pregabalin to prevent seizures, keep taking it even if you feel fine. You may have an increase in seizures if you stop taking pregabalin. Follow your doctor's instructions. You may have withdrawal symptoms when you stop using pregabalin after using it over a long period of time. Withdrawal symptoms include headache, sleep problems, nausea, and diarrhea. Do not stop using pregabalin suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely. Carry an ID card or wear a medical alert bracelet stating that you are taking pregabalin, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking a seizure medication. Store pregabalin at room temperature away from moisture, light, and heat.


What happens if I miss a dose?


Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?


Seek emergency medical treatment if you think you have used too much of this medicine.

Symptoms of a pregabalin overdose are not known.

What should I avoid while taking pregabalin?


Avoid drinking alcohol. It can increase some of the side effects of pregabalin. Pregabalin can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by pregabalin. Tell your doctor if you regularly use any of these other medicines.

Pregabalin side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects:

muscle pain, weakness, or tenderness (especially if you also have a fever and feel tired);

easy bruising or bleeding; or

swelling in your hands or feet, rapid weight gain.

Less serious side effects may include:

dizziness or drowsiness, anxiety;

blurred vision;

loss of balance or coordination;

problems with memory or concentration;

dry mouth;

skin rash or itching;

constipation, stomach pain;

increased appetite; or

joint or muscle pain.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Pregabalin Dosing Information


Usual Adult Dose for Diabetic Neuropathy:

Initial dose: 50 mg 3 times a day

The maximum recommended dose is 100 mg 3 times a day in patients with a creatinine clearance of at least 60 mL/min.

The dose may be increased to 100 mg 3 times a day within 1 week based on efficacy and tolerability.

Usual Adult Dose for Postherpetic Neuralgia:

Initial dose: 75 mg 2 times a day or 50 mg 3 times a day in patients with a creatinine clearance of at least 60 mL/min

The dose may be increased to 100 mg 3 times a day within 1 week based on efficacy and tolerability.

Maximum dose: Patients who do not experience sufficient pain relief following 2 to 4 weeks of treatment with 300 mg/day and who are able to tolerate pregabalin, may be treated with up to 300 mg 2 times a day or 200 mg 3 times a day. Due to the dose-dependent adverse effects and the higher rate of treatment discontinuation due to adverse events, dosing above 300 mg/day should be reserved only for those patients who have ongoing pain and are tolerating 300 mg daily.

Usual Adult Dose for Epilepsy:

Initial dose: 75 mg 2 times a day or 50 mg 3 times a day

Doses of 150 mg to 600 mg/day have been shown to be effective as adjunctive therapy in the treatment of partial onset seizures. The total daily dose should be divided and given either 2 or 3 times a day.

Maximum dose: Based on individual patient response and tolerability, the dose may be increased to a maximum of 600 mg/day.

The efficacy of add-on pregabalin in patients taking gabapentin has not been evaluated in controlled trials. Therefore, dosing recommendations for the use of pregabalin with gabapentin cannot be offered.

Usual Adult Dose for Fibromyalgia:

Initial dose: 75 mg two times a day (150 mg/day)
The dose may be increased to 150 mg two times a day (300 mg/day) within one week based on efficacy and tolerability.

Patients who do not experience sufficient benefit with 300 mg/day may be further increased to 225 mg two times a day (450 mg/day).

Recommended dose: 300 to 450 mg/day

Although pregabalin was also studied at 600 mg/day, there is no evidence that this dose confers additional benefit and this dose was less well tolerated. In view of the dose-dependent adverse reactions, treatment with doses above 450 mg/day is not recommended.

What other drugs will affect pregabalin?


There may be other drugs that can interact with pregabalin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?


Your pharmacist can provide more information about pregabalin.

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