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Antibiotics
    Home > Antibiotics > Megamentin (Augmentin)
 

Megamentin (Augmentin)
Select Ref Description Manufacturer Pack Size Strength Our Price
J558 Megamentin (Augmentin) Generic 6 tabs 625 mg $ 7.02
J501 Amoxicillin Generic 10 caps 500 mg $ 2.80
J348 Amoxicillin Generic 10 caps 250 mg $ 3.48
J40 Augmentin (Amoxicillin Clavulanate) Generic 10 tabs 375 mg $ 7.61
J41 Augmentin (Amoxicillin Clavulanate) Generic 10 tabs 625 mg $ 14.49
J42 Augmentin (Amoxicillin Clavulanate) Generic 4 tabs 1000 mg $ 25.38
P736 Mox (Amoxicillin) Ranbaxy 15 caps 250 mg $ 3.91
P737 Mox (Amoxicillin) Ranbaxy 15 caps 500 mg $ 6.97
P738 Mox Clav (Amoxycillin + Clavulanic Acid) Ranbaxy 10 tabs 250 mg+125 mg $ 13.99
P739 Mox Clav (Amoxycillin + Clavulanic Acid) Ranbaxy 10 tabs 500 mg+125 mg $ 15.97
J295 Trimox (Amoxycillin) Generic 10 caps 500 mg $ 5.25
Price is per pack & not per tab.. eg: if pack size is 10 tabs & price is $2.75 then for 100 tabs the price would be $27.50

What is amoxicillin and clavulanate potassium?


Amoxicillin is an antibiotic in a group of drugs called penicillins. Amoxicillin fights bacteria in the body.

Clavulanate potassium is a form of clavulanic acid, which is similar to penicillin. Clavulanate potassium fights bacteria that is often resistant to penicillins and other antibiotics.

The combination of amoxicillin and clavulanate potassium is used to treat many different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin.

Amoxicillin and clavulanate potassium may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about amoxicillin and clavulanate potassium?


Do not use this medication if you are allergic to amoxicillin or clavulanate potassium, or if you have ever had liver problems caused by this medication. Do not use if you are allergic to any other penicillin antibiotic, such as ampicillin (Omnipen, Principen), carbenicillin (Geocillin), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others.

Before taking amoxicillin and clavulanate potassium, tell your doctor if you have liver disease (or a history of hepatitis or jaundice), kidney disease, or mononucleosis, or if you are allergic to a cephalosporin antibiotic, such as cefdinir (Omnicef), cefprozil (Cefzil), cefuroxime (Ceftin), cephalexin (Keflex), and others.

If you switch from one tablet form to another (regular, chewable, or extended-release tablet), take only the new tablet form and strength prescribed for you. This medicine may not be as effective or could be harmful if you do not use the exact tablet form your doctor has prescribed. Amoxicillin and clavulanate potassium can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Amoxicillin and clavulanate potassium can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking amoxicillin and clavulanate potassium.

What should I discuss with my healthcare provider before taking amoxicillin and clavulanate potassium?


Do not use this medication if you are allergic to amoxicillin or clavulanate potassium, or if you have ever had liver problems caused by this medication. Do not use if you are allergic to any other penicillin antibiotic, such as ampicillin (Omnipen, Principen), carbenicillin (Geocillin), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others.

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking amoxicillin and clavulanate potassium, tell your doctor if you have:

liver disease (or a history of hepatitis or jaundice);

kidney disease;

mononucleosis; or

if you are allergic to a cephalosporin antibiotic, such as cefdinir (Omnicef), cefprozil (Cefzil), cefuroxime (Ceftin), cephalexin (Keflex), and others.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Amoxicillin and clavulanate potassium can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking amoxicillin and clavulanate potassium. Amoxicillin and clavulanate potassium can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The liquid and chewable tablet forms of this medication may contain phenylalanine. Talk to your doctor before using these forms of amoxicillin and clavulanate potassium if you have phenylketonuria (PKU).

How should I take amoxicillin and clavulanate potassium?
Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

If you switch from one tablet form to another (regular, chewable, or extended-release tablet), take only the new tablet form and strength prescribed for you. The strength of clavulanate potassium is not the same among the different tablet forms, even though the amount of amoxicillin may be the same as in the tablet you were using before. This medicine may not be as effective or could be harmful if you do not use the exact tablet form your doctor has prescribed. Take this medicine with a full glass of water. Take the medicine at the start of a meal to reduce stomach upset.

The Augmentin tablet should be swallowed whole.

The Augmentin Chewable tablet must be chewed before swallowing. Do not swallow a chewable tablet whole.

Do not crush or chew the Augmentin XR (extended-release) tablet. Swallow the pill whole, or break the pill in half and take both halves one at a time. If you have trouble swallowing a whole or half pill, talk with your doctor about using another form of amoxicillin and clavulanate potassium. Shake the liquid form of this medicine well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Amoxicillin and clavulanate potassium should be taken at evenly spaced intervals as prescribed. It is important to take amoxicillin and clavulanate potassium regularly to get the most benefit.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Amoxicillin and clavulanate potassium will not treat a viral infection such as the common cold or flu.

This medication can cause you to have false results with certain medical tests, including urine glucose (sugar) tests. Tell any doctor who treats you that you are using amoxicillin and clavulanate potassium.

Store the tablets at room temperature away from moisture and heat. Store the liquid form of this medicine in the refrigerator. Throw away any unused liquid after 10 days.


What happens if I miss a dose?


Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Overdose can cause nausea, vomiting, stomach pain, diarrhea, skin rash, drowsiness, and hyperactivity.

What should I avoid while taking amoxicillin and clavulanate potassium?


Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, stop taking this medication and call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Amoxicillin and clavulanate potassium side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

diarrhea that is watery or has blood in it;

pale or yellowed skin, dark colored urine, fever, confusion or weakness;

easy bruising or bleeding;

skin rash, bruising, severe tingling, numbness, pain, muscle weakness;

agitation, confusion, unusual thoughts or behavior, seizure (convulsions);

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

fever, sore throat, and headache with severe blistering, peeling, or red skin rash.

Less serious side effects may include:

mild diarrhea, gas, stomach pain;

nausea or vomiting;

headache;

skin rash or itching;

white patches in your mouth or throat; or

vaginal yeast infection (itching or discharge).

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Amoxicillin and clavulanate potassium Dosing Information


Usual Adult Dose for Aspiration Pneumonia:

500 mg orally every 8 hours or 875 mg orally every 12 hours
Therapy should be continued until the infiltrate is cleared or a residual scar forms, sometimes for as long as 2 to 4 months, depending on the nature and severity of the infection.

Usual Adult Dose for Bronchitis:

500 mg orally every 8 hours or 875 mg orally every 12 hours for 7 to 10 days

Usual Adult Dose for Febrile Neutropenia:

Low-risk: 500 mg orally every 8 hours in combination with ciprofloxacin until the patient has been afebrile for at least 24 hours and the absolute neutrophil count is more than 500 cells/mm3

Usual Adult Dose for Otitis Media:

250 mg orally every 8 hours or 500 mg orally every 12 hours for 10 to 14 days
For more severe infections, 500 mg orally every 8 hours or 875 mg orally every 12 hours may be administered.

Usual Adult Dose for Pneumonia:

Community-acquired:

Immediate-release tablets: 500 mg orally every 8 hours or 875 mg orally every 12 hours

The duration of therapy for pneumococcal pneumonia is 7 to 10 days. Pneumonia caused by other organisms may require up to 21 days of therapy.

Extended release tablets: 2 g (2 tablets) every 12 hours for 7 to 10 days

Usual Adult Dose for Pyelonephritis:

250 mg orally every 8 hours or 500 mg orally every 12 hours for 14 days

For more severe infections, 500 mg orally every 8 hours or 875 mg orally every 12 hours may be administered.

Usual Adult Dose for Sinusitis:

Immediate-release tablets: 250 mg orally every 8 hours or 500 mg orally every 12 hours for 10 to 14 days

For more severe infections, 500 mg orally every 8 hours or 875 mg orally every 12 hours may be administered. Longer courses of therapy, sometimes 3 or 4 weeks, may be required for refractory or recurrent cases.

Extended release tablets: 2 g (2 tablets) every 12 hours for 10 days

Usual Adult Dose for Skin or Soft Tissue Infection:

250 mg orally every 8 hours or 500 mg orally every 12 hours for 7 days, or for 3 days following resolution of acute inflammation

For more severe infections, 500 mg orally every 8 hours or 875 mg orally every 12 hours may be administered. For more severe infections, such as diabetic soft tissue infections, 14 to 21 days of therapy may be required.

Usual Adult Dose for Upper Respiratory Tract Infection:

250 mg orally every 8 hours or 500 mg orally every 12 hours for 10 days

For more severe infections, 500 mg orally every 8 hours or 875 mg orally every 12 hours may be administered.

Usual Adult Dose for Urinary Tract Infection:

250 mg orally every 8 hours or 500 mg orally every 12 hours for 3 to 7 days

For more severe infections, 500 mg orally every 8 hours or 875 mg orally every 12 hours may be administered.

Usual Pediatric Dose for Melioidosis:

8 years or less: Amoxicillin-clavulanate 30 mg/kg-15 mg/kg per day plus amoxicillin 30 mg/kg/day are recommended after an initial 10 days of parenteral antibiotic therapy

Duration: 20 weeks

Usual Pediatric Dose for Otitis Media:

11 weeks or less:
125 mg/5 mL suspension: 15 mg/kg orally every 12 hours for 10 days

3 months (12 weeks) or older:
39 kg or less:
125 mg/5 mL suspension: 6.7 to 13.3 mg/kg orally, every 8 hours
200 mg/5 mL or 400 mg/5 mL concentrated suspension: 12.5 to 22.5 mg/kg orally every 12 hours

40 kg or more: Use adult dosing guidelines.

Recurrent Otitis Media:

600 mg amoxicillin/42.9 mg clavulanate per 5 mL suspension:
3 months or older and 39 kg or less: 45 mg/kg every 12 hours
40 kg or more: use other forms of suspension

Usual Pediatric Dose for Pneumonia:

11 weeks or less:
125 mg/5 mL suspension: 15 mg/kg orally every 12 hours for 10 days

3 months (12 weeks) or older:
39 kg or less:
125 mg/5 mL suspension or 250 mg/5 mL suspension: 6.7 to 13.3 mg/kg orally every 8 hours
200 mg/5 mL or 400 mg/5 mL concentrated suspension: 12.5 to 22.5 mg/kg orally every 12 hours

40 kg or more: Use adult dosing guidelines.

Usual Pediatric Dose for Sinusitis:

11 weeks or less:
125 mg/5 mL suspension: 15 mg/kg orally every 12 hours for 10 days

3 months (12 weeks) or older:
39 kg or less:
125 mg/5 mL suspension: 6.7 to 13.3 mg/kg orally every 8 hours
200 mg/5 mL or 400 mg/5 mL concentrated suspension: 12.5 to 22.5 mg/kg orally every 12 hours

40 kg or more: Use adult dosing guidelines.

Usual Pediatric Dose for Bacterial Infection:

11 weeks or less:
125 mg/5 mL suspension: 15 mg/kg orally every 12 hours for 10 days

3 months (12 weeks) or older:
39 kg or less:
125 mg/5 mL suspension: 6.7 to 13.3 mg/kg orally, every 8 hours
200 mg/5 mL or 400 mg/5 mL concentrated suspension: 12.5 to 22.5 mg/kg orally every 12 hours

40 kg or more: Use adult dosing guidelines.

Usual Pediatric Dose for Urinary Tract Infection:

11 weeks or less:
125 mg/5 mL suspension: 15 mg/kg orally every 12 hours for 10 days

3 months (12 weeks) or older:
39 kg or less:
125 mg/5 mL suspension: 6.7 to 13.3 mg/kg orally, every 8 hours
200 mg/5 mL or 400 mg/5 mL concentrated suspension: 12.5 to 22.5 mg/kg orally every 12 hours

40 kg or more: Use adult dosing guidelines.

Usual Pediatric Dose for Skin and Structure Infection:

11 weeks or less:
125 mg/5 mL suspension: 15 mg/kg orally every 12 hours for 10 days

3 months (12 weeks) or older:
39 kg or less:
125 mg/5 mL suspension: 6.7 to 13.3 mg/kg orally, every 8 hours
200 mg/5 mL or 400 mg/5 mL concentrated suspension: 12.5 to 22.5 mg/kg orally every 12 hours

40 kg or more: Use adult dosing guidelines.

What other drugs will affect amoxicillin and clavulanate potassium?
Tell your doctor about all other medications you use, especially:

allopurinol (Zyloprim);

probenecid (Benemid); or

another antibiotic (for the same or for a different infection).

This list is not complete and there may be other drugs that can interact with amoxicillin and clavulanate potassium. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?


Your pharmacist can provide more information about amoxicillin and clavulanate potassium.

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