What is Ivabradine?
Ivabradine is a pure heart rate-lowering agent that acts by selective inhibition of the cardiac pacemaker, the current that controls the spontaneous diastolic depolarization in the sinus node and regulates heart rate.
Ivabradine's effects are selective to the sinus node and the new agent has no effect on intracardiac conduction, myocardial contractility or ventricular repolarization.
Unlike beta-blockers, the most common current treatment for angina, Procoralan is free from sexual disturbances, respiratory side effects caused by constriction or spasm of the airways, bradycardia or rebound phenomena. |
