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Anti Depressant
    Home > Anti Depressant > Fluvoxamine
 

Fluvoxamine
Select Ref Description Manufacturer Pack Size Strength Our Price
J436 Fluvoxamine Generic 10 tabs 50 mg $ 17.55
P793 Fluvator (Fluvoxamine Maleate) Torrent 10 tabs 50 mg $ 9.49
P794 Fluvator (Fluvoxamine Maleate) Torrent 10 tabs 100 mg $ 15.97
J212 Luvox (Fluvoxamine Maleate) Generic 10 tabs 50 mg $ 10.17
Price is per pack & not per tab.. eg: if pack size is 10 tabs & price is $2.75 then for 100 tabs the price would be $27.50
What is fluvoxamine?
Fluvoxamine is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Fluvoxamine affects chemicals in the brain that may become unbalanced and cause obsessive-compulsive symptoms.

Fluvoxamine is used to treat social anxiety disorder (social phobia), or obsessive-compulsive disorders involving recurring thoughts or actions.

Fluvoxamine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about fluvoxamine?


Do not take this medication if you are allergic to fluvoxamine, or if you are also taking alosetron (Lotronex), tizanidine (Zanaflex), thioridazine (Mellaril), pimozide (Orap), or an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam). Some of these medications can cause serious or life-threatening drug interactions when taken within 14 days before or after taking fluvoxamine.

You may have thoughts about suicide when you first start taking an this medication, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself. There are many other medicines that can cause serious medical problems if you take them together with fluvoxamine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

What should I discuss with my healthcare provider before taking fluvoxamine?


You should not take this medication if you are allergic to fluvoxamine, or if you are also taking:

alosetron (Lotronex);

tizanidine (Zanaflex);

thioridazine (Mellaril);

pimozide (Orap); or

an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam).

Some of these medications can cause serious or life-threatening drug interactions when taken together with fluvoxamine. You must wait at least 14 days after stopping an MAO inhibitor before you can take fluvoxamine. After you stop taking fluvoxamine, you must wait at least 14 days before you can start taking an MAOI.

Before taking fluvoxamine, tell your doctor if you have:

liver disease;

seizures or epilepsy;

bipolar disorder (manic depression); or

a history of drug abuse or suicidal thoughts.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take fluvoxamine.

You may have thoughts about suicide when you first start taking fluvoxamine, especially if you are younger than 24 years old. Tell your doctor if you have symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

FDA pregnancy category C. This medication may cause serious or life-threatening lung problems in newborn babies whose mothers take the medication during pregnancy. However, you may have a relapse of symptoms if you stop taking fluvoxamine during pregnancy. If you are planning a pregnancy, or if you become pregnant while taking fluvoxamine, do not stop taking the medication without first talking to your doctor. Fluvoxamine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give fluvoxamine to anyone younger than 18 years old without the advice of a doctor.

How should I take fluvoxamine?


Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Do not crush, chew, or open an extended-release capsule. Swallow the pill whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

You may take fluvoxamine with or without food.

Do not stop using fluvoxamine without first talking to your doctor. You may have unpleasant side effects if you stop taking this medication suddenly. Store fluvoxamine at room temperature away from moisture and heat.

What happens if I miss a dose?


Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take extra medicine to make up the missed dose.

What happens if I overdose?


Seek emergency medical attention if you think you have taken too much of this medication. Overdose symptoms may include blurred vision, lack of coordination, extreme drowsiness, nausea and vomiting, fast heart rate, trouble breathing, fainting, and coma.

What should I avoid while taking fluvoxamine?


Avoid drinking alcohol, which can increase some of the side effects of fluvoxamine. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, anxiety or depression can add to sleepiness caused by fluvoxamine. Tell your doctor if you regularly use any of these medicines.
Fluvoxamine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Fluvoxamine side effects
Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have a serious side effect such as:

seizure (convulsions);

unusual thoughts or behavior;

anxiety, restlessness, memory problems, trouble concentrating, hallucinations, feeling like you might pass out;

high fever, chills or goose bumps, loss of coordination, overactive reflexes, stiff muscles; or

confusion, sweating, fast or uneven heartbeats, and rapid breathing.

Less serious side effects may include:

loss of appetite, weight loss;

dry mouth, mild nausea or upset stomach, diarrhea, constipation;

sleep problems (insomnia);

dizziness, drowsiness;

decreased sex drive, impotence, trouble having an orgasm; or

unusual dreams.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Fluvoxamine Dosing Information


Usual Adult Dose for Obsessive Compulsive Disorder:

Initial tablet dose: 50 mg orally once a day at bedtime.
Maintenance dose: 100 to 300 mg per day. The dose may be increased in 50 mg increments every 4 to 7 days, as tolerated, until maximum therapeutic benefit is achieved.
Maximum Dose: 300 mg per day.
It is advisable that a total daily dose of more than 100 mg should be given in two divided doses. If the doses are not equal, the larger dose should be given at bedtime.

Although the efficacy of fluvoxamine tablets beyond 10 weeks of dosing for OCD has not been documented in controlled trials, OCD is a chronic condition, and it is reasonable to consider continuation for a responding patient. Dosage adjustments should be made to maintain the patient on the lowest effective dosage, and patients should be periodically reassessed to determine the need for continued treatment.

Initial extended release capsule dose: 100 mg once per day.
Fluvoxamine extended release capsules should be administered, with or without food, as a single daily dose at bedtime.

In the controlled clinical trials establishing the effectiveness of fluvoxamine extended release capsules in OCD, patients were titrated in 50 mg increments within a dose range of 100 mg/day to 300 mg/day. Consequently, the dose should be increased in 50 mg increments every week, as tolerated, until maximum therapeutic benefit is achieved, not to exceed 300 mg per day.

Although the efficacy of fluvoxamine extended release capsules beyond 12 weeks of dosing for OCD has not been documented in controlled trials, social anxiety disorder is a chronic condition, and it is reasonable to consider continuation for a responding patient. Dosage adjustments should be made to maintain the patient on the lowest effective dosage, and patients should be periodically reassessed to determine the need for continued treatment.

Usual Adult Dose for Depression:

Investigational:
Initial dose: 50 mg orally once a day at bedtime
Maintenance Dose: 100 to 300 mg per day. The dose may be increased in 50 mg increments every 4 to 7 days, as tolerated, until maximum therapeutic benefit is achieved. Total daily doses of more than 100 mg should be given in two divided doses. If the doses are not equal, the larger dose should be given at bedtime.

Usual Adult Dose for Panic Disorder:

Investigational:
Initial dose: 50 mg orally once a day at bedtime
Maintenance Dose: 100 to 300 mg per day. The dose may be increased in 50 mg increments every 4 to 7 days, as tolerated, until maximum therapeutic benefit is achieved. Total daily doses of more than 100 mg should be given in two divided doses. If the doses are not equal, the larger dose should be given at bedtime.

Usual Geriatric Dose for Obsessive Compulsive Disorder:

Initial tablet dose: Due to greater sensitivity to its effects and slower clearance, lower initial doses (25 mg per day at bedtime) may be advisable.
Maintenance dose: 50 to 300 mg per day. Slower titration may be advisable for elderly patients. Total daily doses of more than 100 mg should be given in two divided doses. If the doses are not equal, the larger dose should be given at bedtime.

Although the efficacy of fluvoxamine tablets beyond 10 weeks of dosing for OCD has not been documented in controlled trials, OCD is a chronic condition, and it is reasonable to consider continuation for a responding patient. Dosage adjustments should be made to maintain the patient on the lowest effective dosage, and patients should be periodically reassessed to determine the need for continued treatment.

Initial extended release capsule dose: 100 mg once per day.
Fluvoxamine extended release capsules should be administered, with or without food, as a single daily dose at bedtime.

In the controlled clinical trials establishing the effectiveness of fluvoxamine extended release capsules in OCD, patients were titrated in 50 mg increments within a dose range of 100 mg/day to 300 mg/day. Consequently, the dose should be increased in 50 mg increments every week, as tolerated, until maximum therapeutic benefit is achieved, not to exceed 300 mg per day. Elderly patients have been observed to have a decreased clearance of fluvoxamine maleate. Consequently, it may be appropriate to titrate slowly following the initial dose of 100 mg.

Although the efficacy of fluvoxamine extended release capsules beyond 12 weeks of dosing for OCD has not been documented in controlled trials, social anxiety disorder is a chronic condition, and it is reasonable to consider continuation for a responding patient. Dosage adjustments should be made to maintain the patient on the lowest effective dosage, and patients should be periodically reassessed to determine the need for continued treatment.

Usual Pediatric Dose for Obsessive Compulsive Disorder:

8 to 11 years:
Initial dose: 25 mg orally once a day at bedtime.
Maintenance dose: 25 to 100 mg orally twice a day. The dose may be increased in 25 mg increments every 4 to 7 days, as tolerated, up to a maximum dose of 200 mg per day. Total daily doses of more then 50 mg should be given in two divided doses. If the two divided doses are not equal, the larger dose should be given at bedtime.

11 to 17 years:
Initial dose: 25 mg orally once a day at bedtime.
Maintenance dose: 25 to 150 mg orally twice a day. The dose may be increased in 25 mg increments every 4 to 7 days, as tolerated, up to a maximum dose of 300 mg per day. Total daily doses of more then 50 mg should be given in two divided doses. If the two divided doses are not equal, the larger dose should be given at bedtime.

What other drugs will affect fluvoxamine?


Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin and NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with fluvoxamine may cause you to bruise or bleed easily.

Many drugs can interact with fluvoxamine. Below is just a partial list. Tell your doctor if you are using:

carbamazepine (Carbatrol, Tegretol);

clozapine (Clozaril, FazaClo);

a diuretic (water pill);

linezolid (Zyvox);

lithium (Lithobid, Eskalith);

methadone (Dolophine, Methadose);

mexiletine (Mexitil);

omeprazole (Prilosec);

phenytoin (Dilantin);

propranolol (Inderal, Inderal LA);

quinidine (Quinaglute, Quinidex, Quin-Release);

ramelteon (Rozerem);

St. John's wort;

tacrine (Cognex);

tramadol (Ultram);

tryptophan (also called L-tryptophan);

theophylline (Aerolate, Bronkodyl, Slo-Bid, Theo-Dur);

a blood thinner such as warfarin (Coumadin);

a sedative such as diazepam (Valium), alprazolam (Xanax), midazolam (Versed), or triazolam (Halcion);
almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig);

medicine to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), perphenazine (Trilafon), and others; or

an antidepressant such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Tofranil), and others.

This list is not complete and there are many other medicines that can cause serious medical problems if you take them together with fluvoxamine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Where can I get more information?


Your pharmacist can provide more information about fluvoxamine.

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