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    Home > Antibiotics > Co Trimoxazole

Co Trimoxazole
Select Ref Description Manufacturer Pack Size Strength Our Price
J538 Co Trimoxazole Generic 10 tabs 960 mg $ 1.96
Price is per pack & not per tab.. eg: if pack size is 10 tabs & price is $2.75 then for 100 tabs the price would be $27.50

What is co-trimoxazole?

This is an antibiotic. It is used to prevent and treat a particular chest infection called Pneumocystis Carinii pneumonia. You may hear the doctors and nurses referring to this pneumonia as ‘PCP’. This infection is due to an organism (bug) which is probably present in most people’s lungs. Children who are receiving long term drugs which interfere with the body’s ability to cope with infections may be more at risk from this type of pneumonia. The symptoms of this infection are a raised temperature, rapid breathing and a dry cough.

How is it given?

Co-trimoxazole is given by mouth in tablet or liquid form. When co-trimoxazole is given by mouth, it is usually given to prevent PCP.

It can be given in higher doses into a vein (intravenously) through a cannula, central venous catheter or implantable port to treat PCP.

What are the side effects?

Nausea and vomiting: Anti-sickness drugs can be given to reduce or prevent these symptoms. Please tell your doctor or nurse if your child’s sickness is not controlled or persists.

Bone marrow suppression: Some children are sensitive to co-trimoxazole and this can show itself by a reduction in how well your child’s bone marrow works. This means he or she may become anaemic, bruise or bleed more easily than usual, and have a higher risk of infection. Please tell your doctor if your child seems unusually tired, has bruising or bleeding, or any signs of infection, especially a high temperature.

Children who are sensitive to co-trimoxazole may find that their bone marrow is more likely to be supressed when taking mercaptopurine or thioguanine as well as co-trimoxazole. Your child’s blood count will be checked regularly and individual advice will be given by your doctor.

Allergic reaction: Some children receiving co-trimoxazole have an allergic reaction to the drug. This reaction may be mild to severe. Signs of a mild allergic reaction include skin rashes and itching, high temperature, shivering, redness of the face, a feeling of dizziness or headache. If you see any of these signs, please report them to a doctor or nurse.

Signs of a severe allergic reaction include any of the above, as well as difficulty in breathing or chest pain. If you are in hospital and your child shows signs of an allergic reaction, call a doctor or nurse immediately. If you are at home and your child shows signs of a severe allergic reaction, call an ambulance immediately.

Diarrhoea: Please tell the doctor or nurse if your child has diarrhoea which is not controlled or persists. It is important that your child drinks lots of fluids.

Sensitivity to sunlight: While your child is having co-trimoxazole, their skin may be more sensitive to sunlight. If your child does go out in the sun, always use a good sunblock of SPF25 or higher and ensure they wear a sunhat.

Important information you should know:

Keep the tablets or liquid in a safe place where children cannot reach them.

Tablets and liquids should be stored at room temperature.

It is important to take the dose as directed by the doctor, nurse or pharmacist.

If the co-trimoxazole has to be stopped, it is very important to clearly mark this in your child’s shared care book and to tell the doctor or nurse if your child becomes unwell. In some instances, he or she will need to be treated with other drugs to prevent PCP.

If your child vomits after taking the dose, inform the doctor or nurse as your child may need another one. Do not give them another dose without informing the doctor or nurse.

If you forget to give your child their dose, do not give them a double dose. Inform your doctor or nurse and keep to your child’s regular dose schedule.

If the doctor decides to stop Co-trimoxazole, return any remaining tablets or liquid to the pharmacist. Do not flush them away.

Co-trimoxazole may need to be stopped before some courses of treatment. Please discuss with your doctor, nurse or pharmacist.


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