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Anti Depressant
    Home > Anti Depressant > Sertraline

Select Ref Description Manufacturer Pack Size Strength Our Price
J540 Sertraline Generic 10 tabs 50mg $ 3.60
J539 Sertraline Generic 10 tabs 100mg $ 5.50
Price is per pack & not per tab.. eg: if pack size is 10 tabs & price is $2.75 then for 100 tabs the price would be $27.50

What is Sertraline hydrochloride?

Sertraline hydrochloride is used to treat a variety of mental health problems. It is thought that Sertraline hydrochloride increases the activity and levels of certain chemicals in the brain. This can improve symptoms such as depression and anxiety.

Some people who take Sertraline hydrochloride may find that it intensifies depression and suicidal feelings in the early stages of treatment. These people have an increased risk of self-harm or suicide in the early stages of taking Sertraline hydrochloride. As Sertraline hydrochloride starts to work these risks decrease.

If you are taking Sertraline hydrochloride, or you care for someone who is taking Sertraline hydrochloride, you need to look out for changes in thoughts or behaviour that could be linked to self-harm or suicide.

If you notice any of these changes or are worried about how Sertraline hydrochloride is affecting you or someone you care for, you should contact your prescriber, a mental health professional or NHS Direct as soon as possible.

It is important that you discuss with your prescriber how long it will take before you can expect to feel any benefits from taking Sertraline hydrochloride.

Other information about Sertraline hydrochloride:

People starting treatment with this form of this medicine will normally be prescribed a low dose. The dose will then be gradually increased. This is in order to reduce the chance of side-effects

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Some medicines work best if they are taken at a specific time of day. Getting the most benefit from your medicine can also be affected by what you eat, when you eat and the times at which you take other medicines.

Specific information on when to take Sertraline hydrochloride can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. You can also ask your doctor or pharmacist for information about when to take your medicine.

How to take your medicine

Some medicines have specific instructions about how to take them. This is because they work better when taken correctly. These instructions can include getting the right dose and special instructions for preparing the medicine.

Specific information on how to take Sertraline hydrochloride can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. Alternatively, you can request information about how to take your medicine from your doctor or pharmacist.

If you are having problems taking this form of Sertraline hydrochloride, you should talk to your prescriber or pharmacist. They may be able to give you advice on other ways to take your medicine or other preparations that are easier for you to take.

Taking too much of your medicine

Taking extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems. If you take extra doses of your medicine, you must get medical advice immediately. You may need a test to assess the effect of taking extra doses. This is because the effects of taking too much medicine are very complex so it is very important that you seek medical advice.

Contact your prescriber, pharmacist, specialist clinic or NHS Direct on 0845 46 47 for advice.

Make sure you take all of your medicine containers with you if you are advised to go to hospital.

Stopping your medicine

If you are not having any problems taking this medicine then do not stop taking it, even if you feel better, unless advised to do so by your prescriber. If, however, you find that this medicine is causing you problems then you should talk to your prescriber about your concerns.

If your medical team decides that it is best that you do not take this medicine any more, they may advise that you do not stop Sertraline hydrochloride abruptly. This is because, in some instances, stopping Sertraline hydrochloride abruptly can cause withdrawal symptoms or cause your original condition to return. In these instances, reducing the dose of Sertraline hydrochloride gradually over time may reduce the chances of having these problems.

If you are in any doubt, contact your prescriber, pharmacist, specialist clinic or NHS Direct on 0845 46 47.

Looking after your medicine

The instructions on how you should keep your medicine are on the pharmacy label. It is a good idea to keep your medicine in the original container. This will help to keep your medicine in the best condition and also allow you to check the instructions. Do not take the medicine if the packaging appears to have been tampered with or if the medicine shows any signs of damage. Make sure that the medicine is out of the sight and reach of children.

Specific information on how to look after Sertraline hydrochloride can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. Alternatively, you can request information about how to look after your medicine from your doctor or pharmacist.

You must not take the medicine after the expiry date shown on the packaging. If you have any unused medicine, return it to your pharmacist who will dispose of it safely.

Whether this medicine is suitable for you

Sertraline hydrochloride is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

    are aged over 65 years
    are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
    are having electroconvulsive therapy
    are suffering from low blood volume
    are taking monoamine oxidase inhibitors or have taken them within the last two weeks
    have attempted suicide
    have diabetes
    have epilepsy
    have had bleeding problems
    have liver problems
    have or have had mania
    have or have had thoughts of committing suicide
    have schizophrenia

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for someone under 18 years of age.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests to check that this medicine is not having any undesired effects

Over time it is possible that Sertraline hydrochloride can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Sertraline hydrochloride has become unsuitable, it is important that the prescriber is contacted immediately.


A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.
Very common: More than 1 in 10 people who take Sertraline hydrochloride

    difficulty sleeping
    dry mouth
    feeling dizzy
    sexual dysfunction including ejaculation problems or erectile dysfunction. Sexual dysfunction may affect men and women
    withdrawal symptoms can occur when this medicine is stopped. These include feeling dizzy, paraesthesiae, difficulty sleeping, strange dreams, feeling agitated or anxious, nausea, vomiting, tremors or headaches

Common: More than 1 in 100 people who take Sertraline hydrochloride

    appetite gain
    chest pain
    decreased libido
    eye or eyesight problems
    feeling anxious
    feeling nervous
    hot flushes
    increased muscle tone
    loss of appetite
    muscle pain or tenderness
    skin rash or rashes
    stomach pain
    taste changes
    teeth grinding

Uncommon: More than 1 in 1000 people who take Sertraline hydrochloride

    abnormal thoughts or feelings
    back pain
    breathing difficulties
    changes to weight
    cold sweats
    coordination problems
    dry skin
    ear pain
    faster heart rate
    general feeling of being unwell
    hair loss
    increased salivation
    muscle contractions
    muscle twitching
    muscle weakness
    nose bleed
    passing much more urine than usual
    raised blood pressure
    respiratory tract infection
    speech problems
    swallowing difficulties
    swelling around the eyes
    tongue problems
    unexplained or easy bruising of the skin or mucous membranes
    unexplained or unexpected increase in muscle movement
    urinary problems
    urinary retention
    urinating more often at night
    vaginal bleeding

Rare: More than 1 in 10,000 people who take Sertraline hydrochloride

    abnormal gait
    abnormal laboratory test results
    abnormal muscle movements or problems controlling muscle movement
    abnormal smell of the skin
    behavioural problems such as feelings of hostility, anger, aggression, thoughts of committing suicide or suicidal tendencies - you or your carer must seek immediate medical advice if you have behavioural changes, thoughts of committing suicide or have attempted to commit suicide. Thoughts of committing suicide or suicidal behaviour may also occur soon after stopping treatment with Sertraline hydrochloride
    blood in the stool
    bone problems
    certain types of dermatitis
    conversion disorder
    decreased blood sugar levels
    difficulty speaking
    dose tolerance decreased
    double vision
    ear infection
    enlargement of the pupil
    faster breathing rate
    feeling paranoid
    gastrointestinal problems
    genital discharge
    hair problems
    heart attack
    heart or circulation problems
    heavy or long menstrual periods
    high levels of cholesterol in the blood
    hypersensitivity to external stimuli such as light, noise and physical contact
    inflammation or infection of the mouth or tongue
    injection site problems
    irritation or inflammation of the penis and foreskin
    irritation or inflammation of the vagina and vulva
    mouth or tongue ulcers
    over-sensitivity or fear of light
    psychosis or psychotic-like behaviour or worsening of psychosis or psychotic-like behaviour
    semen abnormal
    sensory problems
    Sertraline hydrochloride dependence
    sleep walking
    slower heart rate
    spasms of the throat
    tooth problems
    urinary hesitation
    urinary incontinence
    urinating less or less often
    vasodilation procedure

The frequency of these side-effects is unknown

    allergic or anaphylactic reactions
    bleeding problems such as gastrointestinal bleeding
    blood in the urine
    blood problems
    blood sugar control changes in diabetics - people with diabetes may be advised to adjust their anti-diabetic therapy
    breast enlargement in men
    extrapyramidal side effects
    face oedema
    feeling restless and inability to sit still
    increased blood sugar levels
    irregular menstrual periods
    joint pain
    liver problems
    mania or mania-like behaviour - seek medical advice if you get mania or mania-like behaviour
    metabolic problems - some metabolic problems may be fatal. Seek medical advice if you develop headaches; concentration or memory problems; weakness; unsteady movement which may lead to falls; hallucinations; fainting or brief loss of consciousness or respiratory arrest
    muscle cramps
    neuroleptic malignant syndrome or serotonin syndrome - symptoms may include a fever, rigidity, confusion, feeling agitated, sweating excessively or diarrhoea
    oedema of the extremities
    photosensitivity skin reaction
    seizures - you or your carer must seek medical advice if you have seizures or there is a change in seizure frequencies
    Stevens-Johnson syndrome
    strange dreams
    thyroid problems
    toxic epidermal necrolysis

The following side effects have been reported in people who have had medicines similar to Sertraline hydrochloride. The frequency of these side-effects in people who take Sertraline hydrochloride is not known

    bone fractures

If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist or nurse.

Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Sertraline hydrochloride:


The following types of medicine may interact with Sertraline hydrochloride:

    cytochrome P450 enzyme inhibitors
    dopamine antagonists
    medicines that act on the central nervous system
    medicines that affect platelet function
    medicines that are metabolised by the cytochrome P450 system
    medicines that can cause bleeding
    monoamine oxidase inhibitors
    non-steroidal anti-inflammatories
    selective serotonin re-uptake inhibitors
    tricyclic antidepressants

This medicine contains sertraline hydrochloride.

We are unable to list all of the ingredients for your medicine here. You should check that you are able to take the ingredients of your medicine, especially if you have any allergies. You should also check whether any of these ingredients are known to have side-effects.

If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Sertraline hydrochloride before, do not take Sertraline hydrochloride. Talk to your prescriber, pharmacist or nurse as soon as possible.


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