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Anti Bacterial
    Home > Anti Bacterial > Vantin (Cefpodoxime, Proxetil)
 

Vantin (Cefpodoxime, Proxetil)
Select Ref Description Manufacturer Pack Size Strength Our Price
J299 Vantin (Cefpodoxime, Proxetil) Generic 10 tabs 100 mg $ 6.17
J300 Vantin (Cefpodoxime, Proxetil) Generic 10 tabs 200 mg $ 13.05
P752 Cefoprox (Cefpodoxime Proxetil) Cipla 10 tabs 100 mg $ 5.40
P753 Cefoprox (Cefpodoxime Proxetil) Cipla 10 tabs 200 mg $ 9.70
Price is per pack & not per tab.. eg: if pack size is 10 tabs & price is $2.75 then for 100 tabs the price would be $27.50

What is Cefpodoxime proxetil?

Cefpodoxime proxetil is an extended spectrum third generation oral cephalosporin, a prodrug of cefpodoxime. The antibacterial action of cefpodoxime is through inhibition of bacterial cell wall synthesis.

Cefpodoxime proxetil is active against gram positive and gram negative bacteria. It is highly stable in presence of beta-lactamase enzymes.

Indications


Cefoprox is indicated for the treatment of the following infections:

Upper respiratory tract infections, including acute otitis media, tonsillitis and pharyngitis.
Acute exacerbations of chronic bronchitis.
Acute community-acquired pneumonia.
Acute uncomplicated gonorrhoea.
Uncomplicated urinary tract infections.
Uncomplicated skin and skin structure infections

Dosage and Administration

Adults (Age 13 years and older):
Upper respiratory tract infections,
100 mg 12 hourly for 5-10 days

Acute exacerbations of chronic bronchitis
200 mg 12 hourly for 10 days

Acute community-acquired pneumonia
200 mg 12 hourly for 14 days

Uncomplicated gonorrhoea
200 mg single dose

Uncomplicated urinary tract infections
100 mg 12 hourly for 7 days

Skin and skin structure infections
400 mg 12 hourly for 7 to 14 days

Children (Age 5 months through 12 years):
Acute otitis media
10 mg/kg (max 400 mg/dose) once daily or 5 mg/kg (max 200 mg/dose) 12 hourly for 10 days.

Pharyngitis and/or tonsillitis
5 mg/kg/dose (max 100 mg/dose) 12 hourly for 5-10 days.

Hepatic Insufficiency

No dosage adjustment is recommended for patients with hepatic insufficiency.

Renal Insufficiency

Dosage of cefpodoxime should be modified according to the degree of renal impairment for patients with creatinine clearance of less than 30 ml/minute.

Contraindications


Cefoprox is contraindicated in individuals who show hypersensitivity to cefpodoxime proxetil, to cephalosportins or other beta-lactamas.

Pregnancy:
Cefpodoxime may be administered to pregnant women only if clearly indicated.

Lactation:
Cefpodoxime is excreted in human milk. A decision should be made whether to discontinue nursing or to discontinue the drug.

Elderly:
No dose adjustment is recommended in elderly patients with normal renal function.

Pediactric Use:
Cefpodoxime proxetil is not recommended for infants under five months of age.

Side Effects


Adverse effects reported in clinical trials are mild and transient and include diarrhoea, nausea, vomiting, abdominal pain, colitis and headache. Rarely hypersensitivity reactions, rash, pruritus, dizziness, thrombocytopenia, leucopenia or eosinophilia may occur.

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